Autism, schizofrenie, ADHD. Perspective convergente

Autism, schizofrenie, ADHD. Perspective convergente

Autism, schizophrenia, ADHD. convergent approaches

Bogdana MICLEA

Over time, continuous efforts have been made to clarify and circumscribe diagnoses of autism, schizophrenia, and attention deficit hyperactivity disorder (ADHD). The diagnostic split between the 3 disorders dominated psychiatry after the 80s, being still used and recognized as such by the diagnostic manuals. Recently a shift and flexibility of the psychiatric paradigm has been noticed. The categorical perspective on mental illness is gradually complemented by the dimensional one. In the last decade, research in the field of neuroscience and psychology has brought evidence in favor of a partial overlap between ADHD, autism and schizophrenia. The hypothesis of a partial overlap can also be supported by non-medical or psychological theorizations, related to common deficits of symbolic structuring of the psyche in achieving a coherent representation of the world and of one’s own person.

Keywords: autism, schizophrenia, ADHD, diagnosis, partial overlap

Published on line: 31/03/2021

American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington, DC.
Ciaramidaro A, Bölte S, Schlitt S, Hainz D, Poustka F, Weber B, Bara BG, Freitag C, Walter H. Schizophrenia and autism as contrasting minds: neural evidence for the hypo-hyper-intentionality hypothesis. Schizophr Bull. 2015 Jan;41(1):171-9. doi: 10.1093/schbul/sbu124. Epub 2014 Sep 9. PMID: 25210055; PMCID: PMC4266299.
Demontis, D., Walters, R. K., Martin, J., Mattheisen, M., Als, T. D., Agerbo, E., Baldursson, G., Belliveau, R., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Cerrato, F., Chambert, K., Churchhouse, C., Dumont, A., Eriksson, N., Gandal, M., Goldstein, J. I., Grasby, K. L., Grove, J., Gudmundsson, O. O., … Neale, B. M. (2019). Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder. Nature genetics, 51(1), 63–75.
DSM History (
Evans B. (2013). How autism became autism: The radical transformation of a central concept of child development în Britain. History of the human sciences, 26(3), 3–31.
Gudmundsson OO, Walters GB, Ingason A, Johansson S, Zayats T, Athanasiu L, Sonderby IE, Gustafsson O, Nawaz MS, Jonsson GF, Jonsson L, Knappskog PM, Ingvarsdottir E, Davidsdottir K, Djurovic S, Knudsen GPS, Askeland RB, Haraldsdottir GS, Baldursson G, Magnusson P, Sigurdsson E, Gudbjartsson DF, Stefansson H, Andreassen OA, Haavik J, Reichborn-Kjennerud T, Stefansson K. Attention-deficit hyperactivity disorder shares copy number variant risk with schizophrenia and autism spectrum disorder. Transl Psychiatry. 2019 Oct 17;9(1):258. doi: 10.1038/s41398-019-0599-y. PMID: 31624239; PMCID: PMC6797719.
Kernbach JM, Satterthwaite TD, Bassett DS, Smallwood J, Margulies D, Krall S, Shaw P, Varoquaux G, Thirion B, Konrad K, Bzdok D. Shared endo-phenotypes of default mode dsfunction în attention deficit/hyperactivity disorder and autism spectrum disorder. Transl Psychiatry. 2018 Jul 17;8(1):133. doi: 10.1038/s41398-018-0179-6. PMID: 30018328; PMCID: PMC6050263.
Le Gall E, Iakimova G. Cognition sociale dans la schizophrénie et les troubles du spectre de l’autisme : points de convergences et différences fonctionnelles [Social cognition în schizophrenia and autism spectrum disorder: Points of convergence and functional differences]. Encephale. 2018 Dec;44(6):523-537. French. doi: 10.1016/j.encep.2018.03.004. Epub 2018 Aug 16. PMID: 30122298.
Lou HC. Paradigm shift în consciousness research: the child’s self-awareness and abnormalities în autism, ADHD and schizophrenia. Acta Paediatr. 2012 Feb;101(2):112-9. doi: 10.1111/j.1651-2227.2011.02456.x. Epub 2011 Sep 23. PMID: 21883452
Manual de Psihiatrie a Copilului și Adolescentului, sub redactia Prof Dr Iuliana Dobrescu, Total Publishing, Volmul 1, Editia a II-a revizuita și adaugita, 2016, Bucuresti
Martinez, G., Mosconi, E., Daban-Huard, C., Parellada, M., Fananas, L., Gaillard, R., Fatjo-Vilas, M., Krebs, M. O., & Amado, I. (2019). „A circle and a triangle dancing together”: Alteration of social cognition în schizophrenia compared to autism spectrum disorders. Schizophrenia research, 210, 94–100.
McPartland, J., & Volkmar, F. R. (2012). Autism and related disorders. Handbook of clinical neurology, 106, 407–418.
Merleau-Ponty M. Vizibilul și invizibilul, Ed. Tact, Cluj-Napoca, 2017
Middeldorp, C. M., Hammerschlag, A. R., Ouwens, K. G., Groen-Blokhuis, M. M., Pourcain, B. S., Greven, C. U., Pappa, I., Tiesler, C., Ang, W., Nolte, I. M., Vilor-Tejedor, N., Bacelis, J., Ebejer, J. L., Zhao, H., Davies, G. E., Ehli, E. A., Evans, D. M., Fedko, I. O., Guxens, M., Hottenga, J. J., … Boomsma, D. I. (2016). A Genome-Wide Association Meta-Analysis of Attention-Deficit/Hyperactivity Disorder Symptoms în Population-Based Pediatric Cohorts. Journal of the American Academy of Child and Adolescent Psychiatry, 55(10), 896–905.e6.
Mihailescu V. Antropologie. Cinci introduceri. Ed Polirom, 2009, pp25-40 ISBN: 978-973-46-1372-4
Pineda-Alhucema W, Aristizabal E, Escudero-Cabarcas J, Acosta-López JE, Vélez JI. Executive Function and Theory of Mind în Children with ADHD: a Systematic Review. Neuropsychol Rev. 2018 Sep;28(3):341-358. doi: 10.1007/s11065-018-9381-9. Epub 2018 Aug 30. PMID: 30168020.
Ricks DM, Wing L. Language, communication, and the use of symbols în normal and autistic children. J Autism Child Schizophr. 1975 Sep;5(3):191-221. doi: 10.1007/BF01538152. PMID: 1174124.
Russel A Barkley, Attention-Deficit Hyperactivity Disorder A Handbook for diagnosis and treatment. Third Edition, 2006, The Guilford Press pp3-76)
Uekermann J, Kraemer M, Abdel-Hamid M, Schimmelmann BG, Hebebrand J, Daum I, Wiltfang J, Kis B. Social cognition în attention-deficit hyperactivity disorder (ADHD). Neurosci Biobehav Rev. 2010 Apr;34(5):734-43. doi: 10.1016/j.neubiorev.2009.10.009. Epub 2009 Oct 24. PMID: 19857516.
Vandekerckhove, M., Bulnes, L. C., & Panksepp, J. (2014). The emergence of primary anoetic consciousness în episodic memory. Frontiers în behavioral neuroscience, 7, 210.
Zhao, H., Nyholt, D.R. Gene-based analyses reveal novel genetic overlap and allelic heterogeneity across five major psychiatric disorders. Hum Genet 136, 263–274 (2017).